Our rankings
Louisville 71%
Louisville #49 vs SMU #76 in our rankings (network centrality).
Louisville vs SMU Prediction
Overall: venue ignored · using games through Oct 31, 2026
Our pick
49
Louisville62%
Louisville62%38%76
SMU
SMUOur pick: Louisville, 62% to win · projected 31–29
Common opponents
Louisville 87%
Louisville by 14.0 points here, from 3 comparisons.
Efficiency
Louisville 56%
Projected Louisville 31, SMU 29 from opponent-adjusted points scored and allowed.
Louisville vs SMU head to head this season
- Louisville W 41–31 home, Sep 19
Louisville and SMU common opponents · 2
Against the same teams: Louisville went 2–0, SMU went 1–1. The edge compares average margins, as played.
| Opponent | Louisville | SMU | Edge |
|---|---|---|---|
 Florida St |
W 44–20 home, Oct 9 | W 27–24 away, Sep 7 | LOU +21.0 |
 Syracuse |
W 34–26 away, Oct 17 | L 27–30 away, Oct 31 | LOU +11.0 |