Our rankings
Louisville 71%
SMU #76 vs Louisville #49 in our rankings (network centrality).
SMU vs Louisville Prediction
Overall: venue ignored · using games through Oct 31, 2026
Our pick
76
SMU38%
SMU38%62%49
Louisville
LouisvilleOur pick: Louisville, 62% to win · projected 29–31
Common opponents
Louisville 87%
Louisville by 14.0 points here, from 3 comparisons.
Efficiency
Louisville 56%
Projected SMU 29, Louisville 31 from opponent-adjusted points scored and allowed.
SMU vs Louisville head to head this season
- SMU L 31–41 away, Sep 19
SMU and Louisville common opponents · 2
Against the same teams: SMU went 1–1, Louisville went 2–0. The edge compares average margins, as played.
| Opponent | SMU | Louisville | Edge |
|---|---|---|---|
 Florida St |
W 27–24 away, Sep 7 | W 44–20 home, Oct 9 | LOU +21.0 |
 Syracuse |
L 27–30 away, Oct 31 | W 34–26 away, Oct 17 | LOU +11.0 |