Our rankings
USC 85%
USC #7 vs Indiana #28 in our rankings (network centrality).
USC vs Indiana Prediction
Overall: venue ignored · using games through Oct 31, 2026
Our pick
Our pick: Indiana, 73% to win · projected 20–30
Common opponents
Indiana 64%
Indiana by 4.5 points here, from 2 comparisons.
Efficiency
Indiana 82%
Projected USC 20, Indiana 30 from opponent-adjusted points scored and allowed.
USC and Indiana common opponents · 2
Against the same teams: USC went 2–0, Indiana went 1–1. The edge compares average margins, as played.
| Opponent | USC | Indiana | Edge |
|---|---|---|---|
 Rutgers |
W 42–35 away, Sep 19 | W 47–15 away, Oct 3 | IU +25.0 |
 Ohio State |
W 30–18 home, Oct 31 | L 15–19 home, Oct 17 | USC +16.0 |