Our rankings
Lions 56%
Bills #11 vs Lions #7 in our rankings (network centrality).
Bills vs Lions Prediction
Overall: venue ignored · using games through Nov 2, 2026
Our pick
Our pick: Bills, 61% to win · projected 35–30
Common opponents
Bills 66%
Bills by 10.0 points here, from 1 comparison.
Efficiency
Bills 61%
Projected Bills 35, Lions 30 from opponent-adjusted points scored and allowed.
Bills vs Lions head to head this season
- Bills W 41–31 home, Sep 17
Bills and Lions common opponents · 0
These teams haven't played any of the same opponents yet.