Our rankings
Patriots 62%
Bills #11 vs Patriots #2 in our rankings (network centrality).
Bills vs Patriots Prediction
Played at Bills · using games through Nov 2, 2026
Our pick
Our pick: Bills, 52% to win · projected 27–24
Common opponents
Patriots 70%
Patriots by 11.0 points here, from 2 comparisons.
Efficiency
Bills 58%
Projected Bills 27, Patriots 24 from opponent-adjusted points scored and allowed.
Bills vs Patriots head to head this season
- Bills L 26–29 home, Oct 4
Bills and Patriots common opponents · 1
Against the same teams: Bills went 1–0, Patriots went 1–0. The edge compares average margins, adjusted 2 points for home field.
| Opponent | Bills | Patriots | Edge |
|---|---|---|---|
 Raiders |
W 33–30 away, Oct 18 | W 45–17 home, Oct 11 | NE +21.0 |