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Broncos vs 49ers Prediction

Overall: venue ignored · using games through Nov 1, 2026

Our pick

Our pick: 49ers, 57% to win · projected 21–24

Our rankings

Broncos 60%

Broncos #1 vs 49ers #5 in our rankings (network centrality).

Common opponents

49ers 59%

49ers by 4.5 points here, from 4 comparisons.

Efficiency

49ers 57%

Projected Broncos 21, 49ers 24 from opponent-adjusted points scored and allowed.

Broncos vs 49ers head to head this season

Broncos and 49ers common opponents · 3

Against the same teams: Broncos went 3–0, 49ers went 3–0. The edge compares average margins, as played.

OpponentBroncos49ersEdge
Rams W 30–26 home, Sep 27 W 27–7 neutral, Sep 10 SF +16.0
Cardinals W 30–16 away, Oct 25 W 36–30 home, Sep 27 DEN +8.0
Seahawks W 17–14 home, Oct 15 W 32–29 away, Oct 11 Even