Our rankings
Lions 56%
Lions #7 vs Bills #11 in our rankings (network centrality).
Lions vs Bills Prediction
Overall: venue ignored · using games through Nov 2, 2026
Our pick
Our pick: Bills, 61% to win · projected 30–35
Common opponents
Bills 66%
Bills by 10.0 points here, from 1 comparison.
Efficiency
Bills 61%
Projected Lions 30, Bills 35 from opponent-adjusted points scored and allowed.
Lions vs Bills head to head this season
- Lions L 31–41 away, Sep 17
Lions and Bills common opponents · 0
These teams haven't played any of the same opponents yet.