Chiefs vs 49ers Prediction

Overall: venue ignored · using games through Nov 2, 2026

57%13

Our pick: 49ers, 57% to win · projected 21–22

Chiefs 54%

Chiefs #10 vs 49ers #13 in our rankings (network centrality).

49ers 69%

49ers by 9.8 points here, from 3 comparisons.

49ers 54%

Projected Chiefs 21, 49ers 22 from opponent-adjusted points scored and allowed.

Chiefs and 49ers common opponents · 3

Against the same teams: Chiefs went 2–2, 49ers went 3–0. The edge compares average margins, as played.

Opponent	Chiefs	49ers	Edge
Seahawks	L 3–20 away, Oct 25	W 32–29 away, Oct 11	SF +20.0
Dolphins	W 24–10 away, Sep 27	W 35–13 home, Sep 20	SF +8.0
Broncos	W 31–10 home, Sep 14 L 24–28 away, Nov 1	W 24–14 home, Oct 4	SF +1.5