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Chargers vs Bills Prediction

Overall: venue ignored · using games through Nov 2, 2026

Our pick

Our pick: Bills, 80% to win · projected 18–32

Our rankings

Bills 93%

Chargers #32 vs Bills #11 in our rankings (network centrality).

Common opponents

Bills 76%

Bills by 13.7 points here, from 3 comparisons.

Efficiency

Bills 80%

Projected Chargers 18, Bills 32 from opponent-adjusted points scored and allowed.

Chargers vs Bills head to head this season

Chargers and Bills common opponents · 2

Against the same teams: Chargers went 0–2, Bills went 2–0. The edge compares average margins, as played.

OpponentChargersBillsEdge
Rams L 9–24 away, Nov 1 W 37–34 away, Oct 12 BUF +18.0
Raiders L 14–26 home, Sep 20 W 33–30 away, Oct 18 BUF +15.0