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Rams vs 49ers Prediction

Overall: venue ignored · using games through Nov 2, 2026

Our pick

Our pick: 49ers, 60% to win · projected 22–24

Our rankings

49ers 74%

Rams #19 vs 49ers #13 in our rankings (network centrality).

Common opponents

49ers 76%

49ers by 14.0 points here, from 3 comparisons.

Efficiency

49ers 54%

Projected Rams 22, 49ers 24 from opponent-adjusted points scored and allowed.

Rams vs 49ers head to head this season

Rams and 49ers common opponents · 2

Against the same teams: Rams went 0–2, 49ers went 2–0. The edge compares average margins, as played.

OpponentRams49ersEdge
Broncos L 26–30 away, Sep 27 W 24–14 home, Oct 4 SF +14.0
Cardinals L 16–18 home, Oct 18 W 36–30 home, Sep 27 SF +8.0