49ers vs Chiefs Prediction

Overall: venue ignored · using games through Nov 2, 2026

43%10

Our pick: 49ers, 57% to win · projected 22–21

Chiefs 54%

49ers #13 vs Chiefs #10 in our rankings (network centrality).

49ers 69%

49ers by 9.8 points here, from 3 comparisons.

49ers 54%

Projected 49ers 22, Chiefs 21 from opponent-adjusted points scored and allowed.

49ers and Chiefs common opponents · 3

Against the same teams: 49ers went 3–0, Chiefs went 2–2. The edge compares average margins, as played.

Opponent	49ers	Chiefs	Edge
Seahawks	W 32–29 away, Oct 11	L 3–20 away, Oct 25	SF +20.0
Dolphins	W 35–13 home, Sep 20	W 24–10 away, Sep 27	SF +8.0
Broncos	W 24–14 home, Oct 4	W 31–10 home, Sep 14 L 24–28 away, Nov 1	SF +1.5