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49ers vs Rams Prediction

Overall: venue ignored · using games through Nov 2, 2026

Our pick

Our pick: 49ers, 60% to win · projected 24–22

Our rankings

49ers 74%

49ers #13 vs Rams #19 in our rankings (network centrality).

Common opponents

49ers 76%

49ers by 14.0 points here, from 3 comparisons.

Efficiency

49ers 54%

Projected 49ers 24, Rams 22 from opponent-adjusted points scored and allowed.

49ers vs Rams head to head this season

49ers and Rams common opponents · 2

Against the same teams: 49ers went 2–0, Rams went 0–2. The edge compares average margins, as played.

Opponent49ersRamsEdge
Broncos W 24–14 home, Oct 4 L 26–30 away, Sep 27 SF +14.0
Cardinals W 36–30 home, Sep 27 L 16–18 home, Oct 18 SF +8.0