Our rankings
49ers 54%
Seahawks #7 vs 49ers #5 in our rankings (network centrality).
Seahawks vs 49ers Prediction
Overall: venue ignored · using games through Nov 1, 2026
Our pick
Toss-up: Seahawks by a hair (50.4%) · projected 23–22
Common opponents
49ers 53%
49ers by 1.5 points here, from 4 comparisons.
Efficiency
Seahawks 52%
Projected Seahawks 23, 49ers 22 from opponent-adjusted points scored and allowed.
Seahawks vs 49ers head to head this season
- Seahawks L 29–32 home, Oct 11
Seahawks and 49ers common opponents · 3
Against the same teams: Seahawks went 1–2, 49ers went 3–0. The edge compares average margins, as played.
| Opponent | Seahawks | 49ers | Edge |
|---|---|---|---|
 Cardinals |
W 31–7 away, Sep 20 | W 36–30 home, Sep 27 | SEA +18.0 |
 Broncos |
L 14–17 away, Oct 15 | W 24–14 home, Oct 4 | SF +13.0 |
 Commanders |
L 31–33 away, Sep 27 | W 23–17 home, Oct 19 | SF +8.0 |